Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.53 |
| ▸ | ACE | P12821 | 8/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28834211 | 0.91 | HRH1 (0.52) | HRH1ACESCN1ASCN2ASCN3A | |
| SCHEMBL28834212 | 0.91 | HRH1 (0.52) | HRH1ACESCN1ASCN2ASCN3A | |
| SCHEMBL23378966 | 0.88 | HRH1 (0.55) | HRH1SCN1ASCN2ASCN3AALDH1A1 | |
| SCHEMBL29862585 | 0.86 | POLB (0.46) | HRH1ACEALDH1A1SMN1; SMN2ACE2 | |
| SCHEMBL23359791 | 0.86 | HRH1 (0.50) | HRH1 | |
| SCHEMBL23378965 | 0.86 | HRH1 (0.50) | HRH1 | |
| SCHEMBL29862580 | 0.86 | HRH1 (0.50) | HRH1 | |
| SCHEMBL23359793 | 0.86 | HRH1 (0.50) | HRH1 | |
| SCHEMBL25665894 | 0.86 | HRH1 (0.50) | HRH1SCN1ASCN2ASCN3A | |
| SCHEMBL28834365 | 0.83 | PREP (0.45) | ACEALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |