Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970698 | 0.90 | BAZ2B (0.54) | BAZ2BALDH1A1MAPTGAACASP1 | |
| SCHEMBL2978681 | 0.89 | SIRT2 (0.44) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL2970394 | 0.88 | SIRT2 (0.44) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL2973482 | 0.88 | SIRT2 (0.44) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL2980535 | 0.88 | SIRT2 (0.44) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL2978359 | 0.87 | DHODH (0.44) | SIRT2BAZ2BALDH1A1POLBKDM4E | |
| SCHEMBL2980633 | 0.87 | SIRT2 (0.43) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL2975810 | 0.86 | SIRT2 (0.42) | SIRT2BAZ2BALDH1A1MAPTGAA | |
| SCHEMBL5374096 | 0.86 | BAZ2B (0.51) | SIRT2BAZ2B | |
| SCHEMBL2966428 | 0.85 | SIRT2 (0.40) | SIRT2BAZ2BALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772245-B2 | Inhibitors of histone deacetylase | MIIKANA THERAPEUTICS, INC. (US) | 2010-08-10 | — | — | US | disclosed |