Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KDR | P35968 | 2/20 | 0.62 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360257 | 1.00 | KMT2A (0.74) | KMT2ATP53MEN1KDRSLC40A1 | |
| SCHEMBL28778056 | 0.89 | KDR (0.62) | KMT2ATP53MEN1KDRTDP1 | |
| SCHEMBL20554412 | 0.86 | KMT2A (0.60) | KMT2ATP53MEN1TDP1HDAC6 | |
| SCHEMBL30132520 | 0.86 | KMT2A (0.60) | KMT2ATP53MEN1TDP1HDAC6 | |
| SCHEMBL31307866 | 0.85 | KMT2A (1.00) | KMT2ATP53MEN1KDRSLC40A1 | |
| SCHEMBL23493914 | 0.85 | KMT2A (1.00) | KMT2ATP53MEN1KDRSLC40A1 | |
| SCHEMBL29158781 | 0.85 | CYP1A2 (0.63) | KMT2ATP53MEN1KDRTDP1 | |
| SCHEMBL29158821 | 0.85 | KMT2A (0.68) | KMT2ATP53MEN1KDRTDP1 | |
| SCHEMBL28891850 | 0.84 | KDR (0.63) | KMT2ATP53MEN1KDRTDP1 | |
| SCHEMBL28434027 | 0.84 | KDR (0.63) | KMT2ATP53MEN1KDRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-B | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-111777593-B | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-114867719-B | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2024-06-25 | — | — | CN | disclosed |
| CN-115925685-B | Triheteroaryltertiary amine and synthesis method thereof | 南昌大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-115925685-A | Tri-heteroaryl tertiary amine and synthesis method thereof | 南昌大学 | 2023-04-07 | — | — | CN | disclosed |
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |