Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 16/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21274185 | 1.00 | CCR4 (0.42) | CCR4CCR5EDNRA | |
| SCHEMBL23213755 | 0.85 | CCR4 (0.39) | CCR4CCR5EDNRA | |
| SCHEMBL29955754 | 0.83 | POLB (0.37) | — | |
| SCHEMBL6057013 | 0.83 | POLB (0.37) | — | |
| SCHEMBL23623967 | 0.81 | CCR4 (0.39) | CCR4CCR5EDNRA | |
| SCHEMBL29952590 | 0.81 | KCNJ1 (0.38) | CCR4EDNRA | |
| SCHEMBL1474575 | 0.81 | KCNJ1 (0.38) | CCR4EDNRA | |
| SCHEMBL1474943 | 0.78 | CCR4 (0.42) | CCR4EDNRA | |
| SCHEMBL21274427 | 0.78 | KCNJ1 (0.33) | — | |
| SCHEMBL29952408 | 0.78 | CCR4 (0.42) | CCR4EDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175043-A1 | PYRIDOPYRIMIDINE DERIVATIVE AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-08-29 | — | — | WO | disclosed |
| EP-4045037-A1 | HETEROARYL-BIPHENYL AMINES FOR THE TREATMENT OF PD-L1 DISEASES | ChemoCentryx, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |