Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | ATAD2 | Q6PL18 | 4/20 | 0.46 |
| ▸ | ITK | Q08881 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 2/20 | 0.41 |
| ▸ | AXL | P30530 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862862 | 1.00 | BRD4 (0.46) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23359969 | 0.99 | BRD4 (0.46) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23359966 | 0.99 | BRD4 (0.46) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23360601 | 0.99 | BRD4 (0.46) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23360561 | 0.91 | BRD4 (0.44) | BRD4ATAD2ITKSYKDYRK1A | |
| Hydrochloric Acid SCHEMBL23360034 | 0.84 | IDH2 (0.41) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23360187 | 0.84 | IDH2 (0.41) | BRD4ATAD2ITKPRKCIAXL | |
| Hydrochloric Acid SCHEMBL23360353 | 0.84 | PRKCI (0.40) | BRD4ATAD2PRKCIAXLIDH2 | |
| Hydrochloric Acid SCHEMBL23360163 | 0.84 | PRKCI (0.40) | BRD4ATAD2PRKCIAXLIDH2 | |
| Hydrochloric Acid SCHEMBL23360166 | 0.84 | PRKCI (0.40) | BRD4ATAD2PRKCIAXLIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867719-A | Pyrrolidine and piperidine compounds | 柳韩洋行 | 2022-08-05 | — | — | CN | disclosed |