Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 11/20 | 0.78 |
| ▸ | TDO2 | P48775 | 11/20 | 0.78 |
| ▸ | FBP1 | P09467 | 4/20 | 0.47 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28465108 | 0.88 | IDO1 (1.00) | IDO1TDO2FBP1 | |
| SCHEMBL29864912 | 0.88 | IDO1 (1.00) | IDO1TDO2FBP1 | |
| SCHEMBL28844754 | 0.87 | IDO1 (0.80) | IDO1TDO2FBP1PTK6CNR1 | |
| SCHEMBL29865139 | 0.87 | IDO1 (0.80) | IDO1TDO2FBP1PTK6CNR1 | |
| SCHEMBL29865133 | 0.86 | IDO1 (0.76) | IDO1TDO2FBP1PTK6NPC1 | |
| SCHEMBL28844603 | 0.86 | IDO1 (0.76) | IDO1TDO2FBP1PTK6NPC1 | |
| SCHEMBL29865086 | 0.82 | IDO1 (0.88) | IDO1TDO2FBP1SLC2A1 | |
| SCHEMBL28844829 | 0.82 | IDO1 (0.88) | IDO1TDO2FBP1SLC2A1 | |
| SCHEMBL29865067 | 0.82 | IDO1 (0.88) | IDO1TDO2FBP1 | |
| SCHEMBL28463204 | 0.82 | IDO1 (0.88) | IDO1TDO2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |