Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.61 |
| ▸ | PPIA | P62937 | 1/20 | 0.49 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346048 | 1.00 | CYP19A1 (0.62) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL371744 | 0.88 | MEN1 (0.65) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL371728 | 0.86 | MEN1 (0.70) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL31418722 | 0.86 | MEN1 (0.70) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL3298587 | 0.84 | MEN1 (0.63) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL544327 | 0.83 | MEN1 (0.59) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL5226904 | 0.82 | MEN1 (0.65) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL6961324 | 0.82 | MEN1 (0.61) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL5440371 | 0.82 | MEN1 (0.65) | CYP19A1MEN1MAPTKMT2ACYP11B1 | |
| SCHEMBL3040587 | 0.82 | CYP19A1 (0.63) | CYP19A1MEN1MAPTKMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460302-A2 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2024-11-13 | — | — | EP | disclosed |
| EP-4274583-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2023133284-A2 | COMPOUNDS AND METHODS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2023-07-13 | — | — | WO | disclosed |
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |