Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25573303 | 1.00 | TYK2 (0.48) | TYK2JAK1JAK2STAT3JAK3 | |
| SCHEMBL25573299 | 0.95 | TYK2 (0.48) | TYK2JAK1MAP3K5 | |
| SCHEMBL27238472 | 0.84 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL29810696 | 0.84 | TYK2 (0.48) | TYK2JAK1 | |
| SCHEMBL25573309 | 0.84 | TYK2 (0.49) | TYK2JAK1JAK2 | |
| SCHEMBL29865961 | 0.84 | TYK2 (0.49) | TYK2JAK1JAK2 | |
| SCHEMBL25573307 | 0.84 | TYK2 (0.57) | TYK2JAK1JAK2STAT3JAK3 | |
| SCHEMBL29810663 | 0.84 | TYK2 (0.48) | TYK2JAK1MAP3K5 | |
| SCHEMBL27238441 | 0.84 | TYK2 (0.48) | TYK2JAK1MAP3K5 | |
| SCHEMBL25573128 | 0.81 | TYK2 (0.53) | TYK2JAK1JAK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294808-A1 | TYK2 INHIBITORS AND USES THEREOF | Sudo Biosciences Limited (GB) | 2023-12-27 | — | — | EP | claimed |
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | claimed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | claimed |
| CN-117242072-A | TYK2 inhibitor and application thereof | 苏多生物科学有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2022175747-A1 | TYK2 INHIBITORS AND USES THEREOF | SUDO BIOSCIENCES LIMITED (GB) | 2022-08-25 | — | — | WO | disclosed |