Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18304782 | 1.00 | KMT2A (0.54) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL31410809 | 0.85 | KMT2A (0.48) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL11883754 | 0.85 | KMT2A (0.50) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL18304735 | 0.82 | KMT2A (0.53) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3763032 | 0.81 | KMT2A (0.65) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL25411835 | 0.80 | KMT2A (0.58) | KMT2AMAPTTP53THRBNPSR1 | |
| SCHEMBL18304807 | 0.80 | KMT2A (0.58) | KMT2AALDH1A1TP53THRBNPSR1 | |
| SCHEMBL18311755 | 0.80 | KMT2A (0.52) | KMT2AMAPTMEN1SMN1; SMN2RAB9A | |
| SCHEMBL28651731 | 0.79 | POLB (0.47) | KMT2AMAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL1528353 | 0.79 | KMT2A (0.57) | KMT2AMAPTRAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997637-B | Aromatic derivative, preparation method and application thereof in medicine | 保仕健生物科技(上海)有限公司 | 2022-09-27 | — | — | CN | disclosed |