Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540970 | 0.82 | KDM4E (0.48) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL2616447 | 0.78 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL29868197 | 0.78 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL4751136 | 0.78 | KDM4E (0.52) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL25418887 | 0.77 | KDM4E (0.43) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL31708133 | 0.77 | KDM4E (0.43) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL30471977 | 0.77 | KDM4E (0.43) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL30471931 | 0.77 | KDM4E (0.44) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL25216340 | 0.75 | KDM4E (0.42) | KDM4EGAAPDPK1CYP3A4CYP1A2 | |
| SCHEMBL23797047 | 0.75 | KDM4E (0.53) | KDM4EGAAPDPK1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929683-A | Pyridine derivatives as calcium-activated chloride channel modulators | 跨膜蛋白16A有限公司 | 2022-08-19 | — | — | CN | disclosed |