⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993 | 1.00 | — | — | |
| SCHEMBL30808383 | 1.00 | — | — | |
| SCHEMBL27879484 | 1.00 | — | — | |
| SCHEMBL28184335 | 1.00 | — | — | |
| SCHEMBL22434925 | 1.00 | — | — | |
| SCHEMBL18458273 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5741335 | 0.95 | — | — | |
| Charcoal, Activated SCHEMBL10756751 | 0.95 | — | — | |
| Bromide SCHEMBL10876007 | 0.95 | — | — | |
| Ammonia Solution, Strong SCHEMBL22117290 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4320101-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| EP-4281463-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | JANSSEN Pharmaceutica NV (BE) | 2023-11-29 | — | — | EP | disclosed |
| US-20230108125-A1 | SMALL MOLECULE COMPOUNDS | APERTOR PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| WO-2022216900-A2 | SYNTHESIS OF RAPAMYCIN ANALOG COMPOUNDS | Revolution Medicines, Inc. (US) | 2022-10-13 | — | — | WO | disclosed |
| WO-2022159976-A1 | RAPAMYCIN ANALOGS AND USES THEREOF | ANAKURIA THERAPEUTICS, INC. (US) | 2022-07-28 | — | — | WO | disclosed |