Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23327195 | 1.00 | TYK2 (0.48) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL23327407 | 0.85 | TYK2 (0.48) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL30548443 | 0.85 | TYK2 (0.48) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL23327397 | 0.84 | TYK2 (0.46) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL23327701 | 0.80 | TYK2 (0.56) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL30548451 | 0.80 | TYK2 (0.56) | TYK2PDE4DSTAT3JAK1 | |
| SCHEMBL23327694 | 0.80 | TYK2 (0.47) | TYK2PDE4D | |
| SCHEMBL30548439 | 0.78 | TYK2 (0.65) | TYK2PDE4DJAK1 | |
| SCHEMBL23327427 | 0.78 | TYK2 (0.65) | TYK2PDE4DJAK1 | |
| SCHEMBL23327557 | 0.78 | MAPT (0.45) | TYK2PDE4DSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929226-B | TYK2 pseudokinase ligands | 温缇克斯生物科学公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-4054581-A1 | TYK2 PSEUDOKINASE LIGANDS | Ventyx Biosciences, Inc. (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114929226-A | TYK2 pseudokinase ligands | 温缇克斯生物科学公司 | 2022-08-19 | — | — | CN | disclosed |