Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.83 |
| ▸ | LCK | P06239 | 18/20 | 0.83 |
| ▸ | EGFR | P00533 | 10/20 | 0.83 |
| ▸ | BTK | Q06187 | 4/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459578 | 1.00 | JAK3 (0.83) | JAK3LCKEGFRBTK | |
| SCHEMBL23459577 | 1.00 | JAK3 (0.83) | JAK3LCKEGFRBTK | |
| SCHEMBL29871796 | 0.91 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763889 | 0.91 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763891 | 0.91 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL23460258 | 0.90 | JAK3 (0.82) | JAK3LCKEGFRBTK | |
| SCHEMBL23460262 | 0.90 | JAK3 (0.82) | JAK3LCKEGFRBTK | |
| SCHEMBL29871751 | 0.90 | JAK3 (0.82) | JAK3LCKEGFRBTK | |
| SCHEMBL21855219 | 0.89 | JAK3 (0.78) | JAK3LCKEGFRBTK | |
| SCHEMBL21855188 | 0.87 | JAK3 (0.82) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069237-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | Nurix Therapeutics, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |