Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.61 |
| ▸ | MELK | Q14680 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.61 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249985 | 1.00 | BCL6 (0.61) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL20284384 | 0.92 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267153 | 0.92 | BCL6 (0.68) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267138 | 0.91 | BCL6 (0.63) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL20284376 | 0.91 | BCL6 (0.62) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23250084 | 0.91 | BCL6 (0.75) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267505 | 0.90 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267504 | 0.90 | BCL6 (0.65) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL23267037 | 0.90 | BCL6 (0.64) | BCL6MELKNCOR2CHRM4BCL6B | |
| SCHEMBL24718013 | 0.89 | BCL6 (0.61) | BCL6MELKNCOR2CHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605387-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| CN-118388454-A | Modulators of BCL6 proteolysis and related methods of use | 阿尔维纳斯运营股份有限公司 | 2024-07-26 | — | — | CN | disclosed |
| WO-2024086759-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |
| EP-4045496-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | Arvinas Operations, Inc. (US) | 2022-08-24 | — | — | EP | disclosed |