Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 19/20 | 1.00 |
| ▸ | MAP4K2 | Q12851 | 19/20 | 1.00 |
| ▸ | ABL1 | P00519 | 3/20 | 1.00 |
| ▸ | BMX | P51813 | 3/20 | 1.00 |
| ▸ | BCR | P11274 | 1/20 | 1.00 |
| ▸ | RIPK1 | Q13546 | 1/20 | 1.00 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 1.00 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.81 |
| ▸ | LCK | P06239 | 1/20 | 0.78 |
| ▸ | FES | P07332 | 1/20 | 0.78 |
| ▸ | RET | P07949 | 1/20 | 0.78 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.78 |
| ▸ | KIT | P10721 | 1/20 | 0.78 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.78 |
| ▸ | SRC | P12931 | 1/20 | 0.78 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.78 |
| ▸ | FLT1 | P17948 | 1/20 | 0.78 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.78 |
| ▸ | EPHA3 | P29320 | 1/20 | 0.78 |
| ▸ | KDR | P35968 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135042 | 1.00 | TNK2 (1.00) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL29404264 | 1.00 | TNK2 (1.00) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3132435 | 0.96 | TNK2 (0.92) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3139165 | 0.94 | TNK2 (0.89) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3132500 | 0.94 | TNK2 (0.88) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3136175 | 0.93 | TNK2 (0.90) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3137360 | 0.93 | TNK2 (0.88) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL13521779 | 0.93 | TNK2 (0.93) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3134169 | 0.93 | TNK2 (1.00) | TNK2MAP4K2ABL1BMXBCR | |
| SCHEMBL3132265 | 0.92 | TNK2 (0.84) | TNK2MAP4K2ABL1BMXBCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110151767-B | Application of GNF-7 in preparation of medicine for treating influenza virus infection | 武汉威立得生物医药有限公司 | 2022-10-18 | — | — | CN | disclosed |