Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 4/20 | 0.52 |
| ▸ | NMT2 | O60551 | 3/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.49 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727649 | 0.94 | NMT1 (0.52) | NMT1NMT2FOLH1NOD1CPB2 | |
| SCHEMBL11644225 | 0.92 | FOLH1 (0.54) | NMT1NMT2FOLH1NOD1CPB2 | |
| SCHEMBL11644217 | 0.92 | FOLH1 (0.54) | NMT1NMT2FOLH1NOD1CPB2 | |
| SCHEMBL1711244 | 0.92 | FOLH1 (0.57) | FOLH1NOD1CPB2SLC6A5SLC15A2 | |
| SCHEMBL29511099 | 0.92 | FOLH1 (0.57) | FOLH1NOD1CPB2SLC6A5SLC15A2 | |
| SCHEMBL29368554 | 0.92 | FOLH1 (0.57) | FOLH1NOD1CPB2SLC6A5SLC15A2 | |
| SCHEMBL29563714 | 0.92 | FOLH1 (0.57) | FOLH1NOD1CPB2SLC6A5SLC15A2 | |
| SCHEMBL1711242 | 0.92 | FOLH1 (0.57) | FOLH1NOD1CPB2SLC6A5SLC15A2 | |
| SCHEMBL29405941 | 0.91 | FOLH1 (0.55) | NMT1NMT2FOLH1NOD1CPB2 | |
| Benzene SCHEMBL28095115 | 0.89 | FOLH1 (0.54) | FOLH1NOD1CPB2SLC6A5SLC15A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925878-A | Endostatin fragments and variants for the treatment of fibrosis | 艾比欧公司 | 2023-04-07 | — | — | CN | claimed |
| US-11912755-B2 | Endostatin fragments and variants for use in treating fibrosis | BIO, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-115925878-A | Endostatin fragments and variants for the treatment of fibrosis | 艾比欧公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-107849117-B | Endostatin fragments and variants for the treatment of fibrosis | 艾比欧公司 | 2022-08-26 | — | — | CN | disclosed |