Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 13/20 | 1.00 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273512 | 1.00 | NR1H4 (1.00) | NR1H4ELANESIRT3MEN1MAPT | |
| SCHEMBL273743 | 0.91 | NR1H4 (1.00) | NR1H4ELANEMEN1MAPTKMT2A | |
| SCHEMBL29881422 | 0.91 | NR1H4 (1.00) | NR1H4ELANEMEN1MAPTKMT2A | |
| SCHEMBL275111 | 0.90 | NR1H4 (1.00) | NR1H4SIRT3MEN1MAPTKMT2A | |
| SCHEMBL274733 | 0.90 | NR1H4 (0.82) | NR1H4ELANESIRT3MEN1MAPT | |
| SCHEMBL274595 | 0.88 | NR1H4 (1.00) | NR1H4MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29880800 | 0.88 | NR1H4 (1.00) | NR1H4MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL688597 | 0.86 | NR1H4 (0.76) | NR1H4ALDH1A1 | |
| SCHEMBL273855 | 0.84 | NR1H4 (0.75) | NR1H4ELANEMEN1MAPTKMT2A | |
| SCHEMBL274620 | 0.81 | NR1H4 (0.83) | NR1H4ELANEMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |