Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886566 | 1.00 | NR1H4 (0.53) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL1882375 | 0.92 | KMT2A (0.51) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL3459461 | 0.89 | KMT2A (0.48) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL1888275 | 0.88 | NR1H4 (0.68) | NR1H4KMT2ATP53MAPTALDH1A1 | |
| SCHEMBL29880653 | 0.88 | NR1H4 (0.68) | NR1H4KMT2ATP53MAPTALDH1A1 | |
| SCHEMBL29880964 | 0.88 | NR1H4 (0.59) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL1886278 | 0.88 | NR1H4 (0.59) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL29880494 | 0.87 | NR1H4 (0.54) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL1883111 | 0.87 | NR1H4 (0.54) | NR1H4KMT2ARAB9ATP53PKM | |
| SCHEMBL1894949 | 0.84 | NR1H4 (0.72) | NR1H4KMT2AMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |