Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.75 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889937 | 1.00 | NR1H4 (0.75) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL29880659 | 0.96 | NR1H4 (0.80) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL1894116 | 0.96 | NR1H4 (0.80) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL29881075 | 0.92 | NR1H4 (0.62) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL1883064 | 0.92 | NR1H4 (0.62) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL1882207 | 0.89 | NR1H4 (0.80) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL29881681 | 0.89 | NR1H4 (0.80) | NR1H4LMNAKMT2ATSHRHPGD | |
| SCHEMBL1886278 | 0.88 | NR1H4 (0.59) | NR1H4LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL29880964 | 0.88 | NR1H4 (0.59) | NR1H4LMNAKMT2ATSHRALDH1A1 | |
| SCHEMBL1894860 | 0.88 | NR1H4 (0.66) | NR1H4LMNAKMT2ATSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110404073-B | Methods and pharmaceutical compositions for treating hepatitis B virus infection | 国家医疗保健研究所 | 2022-08-16 | — | — | CN | disclosed |