Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608365 | 1.00 | KDM1A (0.39) | KDM1AGRIN2BGRIN2CDDB1CRBN | |
| SCHEMBL31498912 | 0.86 | NR1H2 (0.34) | KDM1AGRIN2BGRIN2CDDB1CRBN | |
| SCHEMBL23609353 | 0.86 | NR1H2 (0.34) | KDM1AGRIN2BGRIN2CDDB1CRBN | |
| SCHEMBL27019991 | 0.82 | KDM1A (0.36) | KDM1AGRIN2BGRIN2CBUB1ALDH1A1 | |
| SCHEMBL30045488 | 0.80 | — | — | |
| SCHEMBL23580721 | 0.80 | — | — | |
| SCHEMBL23580614 | 0.77 | KDM1A (0.31) | KDM1ADDB1CRBNBUB1 | |
| SCHEMBL23580616 | 0.77 | KDM1A (0.31) | KDM1ADDB1CRBNBUB1 | |
| SCHEMBL23608548 | 0.77 | KDM1A (0.31) | KDM1ADDB1CRBNBUB1 | |
| SCHEMBL27020017 | 0.77 | DDB1 (0.35) | KDM1ADDB1CRBNBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114945571-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2022-08-26 | — | — | CN | disclosed |