Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23608479 | 1.00 | KMT2A (0.42) | KMT2ALMNAAAK1ATRBRD9 | |
| SCHEMBL23608695 | 0.85 | BRD9 (0.42) | KMT2ALMNAAAK1BRD9CYP17A1 | |
| SCHEMBL29882548 | 0.85 | BRD9 (0.42) | KMT2ALMNAAAK1BRD9CYP17A1 | |
| SCHEMBL926280 | 0.83 | ATR (0.45) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL29602020 | 0.83 | ATR (0.45) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL29692379 | 0.80 | ATR (0.49) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL23015240 | 0.80 | ATR (0.49) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL23015391 | 0.79 | ATR (0.42) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL29907839 | 0.79 | ATR (0.42) | KMT2ALMNAATRBRD9CYP17A1 | |
| SCHEMBL24195947 | 0.76 | AAK1 (0.41) | AAK1CYP17A1RXFP1METAP1APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-B | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114945571-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2022-08-26 | — | — | CN | disclosed |