SCHEMBL298833

SCHEMBL298833

O=C1C=CC=N[N]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL255876 0.69
SCHEMBL3676724 0.67
Charcoal, Activated SCHEMBL29797978 0.67
SCHEMBL30923519 0.67
Selenium SCHEMBL29864615 0.67
SCHEMBL28735200 0.67
SCHEMBL8539697 0.65
SCHEMBL3861654 0.65
SCHEMBL8629759 0.64
Hydrochloric Acid SCHEMBL30279568 0.57

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107849018-B Piperazine derivatives 安斯泰来制药株式会社 2021-02-23 CN claimed
US-10791743-B2 EC formulations comprising organophosphate insecticides SIPCAM OXON S.P.A. (IT) 2020-10-06 US claimed
EP-3333165-B1 PIPERAZINE DERIVATIVE ASTELLAS PHARMA INC (JP) 2019-09-18 EP claimed
US-10301286-B2 Piperazine derivative ASTELLAS PHARMA INC. (JP) 2019-05-28 US claimed
EP-3333165-A1 PIPERAZINE DERIVATIVE Astellas Pharma Inc. (JP) 2018-06-13 EP claimed
US-20180139963-A1 EC FORMULATIONS COMPRISING ORGANOPHOSPHATE INSECTICIDES SIPCAM OXON S.P.A. (IT) 2018-05-24 US claimed
US-20180139964-A1 EC FORMULATIONS COMPRISING ORGANOPHOSPHATE INSECTICIDES SIPCAM SOCIETÁ ITALIANA PRODOTTI CHIMICI E PER L'AGRICOLTURA MILANO S.P.A. (IT) 2018-05-24 US claimed
EP-3294060-A1 EC FORMULATIONS COMPRISING ORGANOPHOSPHATE INSECTICIDES S.I.P.C.A.M. Società Italiana Prodotti Chimici e Per L' Agricoltura Milano S.p.A (IT) 2018-03-21 EP claimed
WO-2016180658-A1 EC FORMULATIONS COMPRISING ORGANOPHOSPHATE INSECTICIDES SIPCAM SOCIETÀ ITALIANA PRODOTTI CHIMICI E PER L'AGRICOLTURA MILANO S.P.A. (IT) 2016-11-17 WO claimed
EP-2654748-B1 INDAZOLE DERIVATIVES USEFUL AS ERK INHIBITORS MERCK SHARP & DOHME (US) 2016-07-27 EP claimed
US-5185335-A Administer to mammals to stimulate gastrointestinal motility JANSSEN PHARMACEUTICA N.V. (BE) 1993-02-09 US claimed
EP-0370902-B1 USE OF CHROMANE DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF DEPRESSIVE CONDITIONS ELF SANOFI (FR) 1992-08-26 EP claimed
EP-0489300-A2 Tetralones with pharmacological activity J. URIACH &amp; CIA. S.A. (ES) 1992-06-10 EP claimed
EP-0450487-A1 Benzoxazine derivatives, method for their preparation and their use for treating or prophylaxis of diseases HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-09 EP claimed
EP-0445862-A2 N-(4-piperidinyl)(dihydrobenzofuran or dihydro-2H-benzopyran)carboxamide derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1991-09-11 EP claimed
US-5043352-A Chroman derivatives for the treatment of depressive states SANOFI (FR) 1991-08-27 US claimed
US-4931454-A Azachroman derivatives with effects on the cardiovascular system MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1990-06-05 US claimed
EP-0370902-A2 Use of chromane derivatives in the preparation of a medicament for the treatment of depressive conditions ELF SANOFI (FR) 1990-05-30 EP claimed
US-4736026-A REATING A 2-AMINOTHIAZOL-4-YL-2(SYN)-ALKOXYIMINOACETAMIDE AND A 7-AMINO-3-HET-METHYL-3-CEPHEM-4-CARBOXYLATE USING BORON TRIFLUORIDE CATALYST AND SOLVENT TOYAMA CHEMICAL CO., LTD. (JP) 1988-04-05 US claimed
US-4614819-A REACTING A THIOL ESTER COMPOUND WITH 7-AMINOCEPHALOSPORIN IN PRESENCE OF BORON TRIFLUORIDE TOYAMA CHEMICAL CO., LTD. (JP) 1986-09-30 US claimed