Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.69 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.69 |
| ▸ | TOP2A | P11388 | 2/20 | 0.64 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22056134 | 1.00 | HSP90AA1 (0.69) | HSP90AA1HKDC1TOP2AATG4BSLC2A1 | |
| SCHEMBL22056641 | 0.88 | HSP90AA1 (0.77) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 | |
| SCHEMBL9321789 | 0.88 | HSP90AA1 (0.77) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 | |
| SCHEMBL12680567 | 0.82 | HSP90AA1 (0.76) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 | |
| SCHEMBL12680569 | 0.81 | HSP90AA1 (1.00) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 | |
| SCHEMBL9320172 | 0.81 | HSP90AA1 (0.77) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 | |
| SCHEMBL22056829 | 0.80 | TOP2A (0.72) | HSP90AA1HKDC1TOP2AATG4BSLC2A1 | |
| SCHEMBL9320842 | 0.80 | TOP2A (0.72) | HSP90AA1HKDC1TOP2AATG4BSLC2A1 | |
| SCHEMBL29882840 | 0.80 | TOP2A (0.72) | HSP90AA1HKDC1TOP2AATG4BSLC2A1 | |
| SCHEMBL17987719 | 0.78 | TOP2A (1.00) | HSP90AA1HKDC1TOP2ASLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115197126-A | Novel NMNAT enzyme agonist and preparation and application thereof | 清华大学 | 2022-10-18 | — | — | CN | claimed |
| CN-115197126-A | Novel NMNAT enzyme agonist and preparation and application thereof | 清华大学 | 2022-10-18 | — | — | CN | disclosed |