Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 20/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 19/20 | 0.59 |
| ▸ | PRKCB | P05771 | 3/20 | 0.54 |
| ▸ | PRKCH | P24723 | 3/20 | 0.54 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.54 |
| ▸ | LCK | P06239 | 2/20 | 0.54 |
| ▸ | LYN | P07948 | 2/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2973541 | 0.92 | PRKCQ (0.59) | PRKCQPRKCD | |
| SCHEMBL2988563 | 0.89 | PRKCQ (0.73) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2973545 | 0.81 | PRKCQ (0.73) | PRKCQPRKCD | |
| SCHEMBL2975987 | 0.79 | PRKCQ (0.77) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2934363 | 0.78 | PRKCQ (0.77) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2986082 | 0.77 | PRKCQ (0.83) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2976830 | 0.77 | PRKCQ (0.81) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2983700 | 0.77 | PRKCQ (0.60) | PRKCQPRKCD | |
| SCHEMBL2986079 | 0.76 | PRKCQ (0.80) | PRKCQPRKCDPRKCBPRKCHPRKCE | |
| SCHEMBL2977044 | 0.75 | PRKCQ (0.80) | PRKCQPRKCDPRKCBPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | claimed |