Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.61 |
| ▸ | NMT1 | P30419 | 5/20 | 0.46 |
| ▸ | NMT2 | O60551 | 4/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | GNPAT | O15228 | 1/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.41 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30099451 | 0.97 | FOLH1 (0.62) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL29590473 | 0.96 | FOLH1 (0.56) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL30099702 | 0.95 | FOLH1 (0.62) | FOLH1NMT1NMT2TLR2DPP8 | |
| SCHEMBL28526628 | 0.95 | FOLH1 (0.57) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL1373284 | 0.95 | FOLH1 (0.61) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL17371487 | 0.94 | FOLH1 (0.54) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL28081124 | 0.93 | FOLH1 (0.59) | FOLH1NMT1NMT2TLR2DPP4 | |
| SCHEMBL30394354 | 0.93 | FOLH1 (0.66) | FOLH1DPP4DPP8DPP9GSR | |
| SCHEMBL397256 | 0.93 | FOLH1 (0.69) | FOLH1DPP4DPP8DPP9GSR | |
| SCHEMBL7563962 | 0.93 | FOLH1 (0.69) | FOLH1DPP4DPP8DPP9GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4294431-A1 | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES | Vaccitech North America, Inc. (US) | 2023-12-27 | — | — | EP | claimed |
| WO-2022177993-A1 | SELF-ASSEMBLING NANOPARTICLES BASED ON AMPHIPHILIC PEPTIDES | VACCITECH NORTH AMERICA, INC. (US) | 2022-08-25 | — | — | WO | claimed |
| US-20230158117-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF HYPERLIPIDEMIA COMPRISING TRIGONAL GLUCAGON/GLP-1/GIP RECEPTOR AGONIST OR CONJUGATE THEREOF AND METHOD USING THE SAME | HANMI PHARM. CO., LTD. (KR) | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230158117-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF HYPERLIPIDEMIA COMPRISING TRIGONAL GLUCAGON/GLP-1/GIP RECEPTOR AGONIST OR CONJUGATE THEREOF AND METHOD USING THE SAME | GLP1R, GIPR, GCGR | FOLH1 146/4885NMT1 915/4885NMT2 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.