SCHEMBL29888155

SCHEMBL29888155

Cc1cc(Cn2c(=O)[nH]c3ncc(-c4ccccc4C)cc32)no1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 20/20 1.00
GRIN1 Q05586 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20134472 1.00 GRIN2B (1.00) GRIN2BGRIN1
SCHEMBL29887570 0.89 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134114 0.89 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134418 0.88 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL29888207 0.88 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134541 0.88 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL29888037 0.88 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134559 0.83 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134182 0.82 GRIN1 (1.00) GRIN2BGRIN1
SCHEMBL20134252 0.81 GRIN1 (1.00) GRIN2BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989164-B Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2024-08-13 CN claimed
CN-114989164-A Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2022-09-02 CN claimed
CN-114989164-B Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2024-08-13 CN disclosed