SCHEMBL29888652

SCHEMBL29888652

Cc1cc(-c2cnc3[nH]c(=O)n(Cc4cnccc4C)c3c2)ccc1F

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 20/20 1.00
GRIN2B Q13224 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20134359 1.00 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL29887540 0.94 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20134245 0.94 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL29887532 0.90 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20134364 0.90 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL29887602 0.89 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20134362 0.89 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20134289 0.88 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL29887717 0.88 GRIN1 (1.00) GRIN1GRIN2B
SCHEMBL20134295 0.86 GRIN1 (1.00) GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989164-B Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2024-08-13 CN claimed
CN-114989164-A Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2022-09-02 CN claimed
CN-114989164-B Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof 詹森药业有限公司 2024-08-13 CN disclosed