Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.49 |
| ▸ | CDK9 | P50750 | 17/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2993759 | 0.97 | IKBKB (0.55) | IKBKBCHUKCYP2C9CCNT1CDK9 | |
| SCHEMBL2990002 | 0.89 | MAP3K5 (0.63) | IKBKBCHUKCYP2C9CCNT1CDK9 | |
| SCHEMBL2992991 | 0.86 | IKBKB (0.68) | IKBKBCHUKCYP2C9CCNT1CDK9 | |
| Formic Acid SCHEMBL2985060 | 0.83 | IKBKB (0.49) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL13241041 | 0.83 | CCNT1 (0.57) | CCNT1CDK9 | |
| SCHEMBL2990331 | 0.81 | CCNT1 (0.49) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL2990332 | 0.80 | IKBKB (0.57) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL2994638 | 0.79 | CCNT1 (0.48) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL2994635 | 0.78 | IKBKB (0.52) | IKBKBCHUKCCNT1CDK9 | |
| SCHEMBL2985661 | 0.78 | MAP3K5 (0.72) | IKBKBCHUKCYP2C9CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179139-A1 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | BAMBOROUGH PAUL | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179139-A1 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | NFKBIA, PACSIN2, MAP3K2 | IKBKB 11/4885CHUK 22/4885CYP2C9 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.