Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 12/20 | 0.64 |
| ▸ | PDCD1 | Q15116 | 10/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863767 | 1.00 | CD274 (0.64) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL18863838 | 0.86 | CD274 (0.64) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL18727806 | 0.81 | CD274 (0.67) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL18979829 | 0.81 | CD274 (0.67) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL31644196 | 0.81 | CD274 (0.67) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL18792069 | 0.81 | CD274 (0.67) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL20999484 | 0.80 | CD274 (0.48) | CD274PDCD1MAPTKDM4ENPC1 | |
| SCHEMBL17161578 | 0.77 | CD274 (0.79) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL19731928 | 0.77 | CD274 (0.63) | CD274PDCD1MAPTHSD17B10ALOX15 | |
| SCHEMBL20356610 | 0.75 | CD274 (0.64) | CD274PDCD1MAPTHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641885-B | Heterocyclic compounds as immunomodulators | 因赛特公司 | 2022-09-30 | — | — | CN | disclosed |