Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | POLB | P06746 | 6/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | STAT1 | P42224 | 1/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 7/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627763 | 1.00 | KDM4E (0.76) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL7758792 | 0.90 | KDM4E (0.60) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL30566340 | 0.89 | MAPT (0.64) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL29069240 | 0.89 | MAPT (0.64) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL29069220 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL30566362 | 0.88 | MAPT (0.65) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL29069246 | 0.87 | MAPT (0.68) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL30566350 | 0.87 | MAPT (0.68) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL18880260 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1MAPTPOLBRAB9A | |
| SCHEMBL29853686 | 0.87 | KDM4E (1.00) | KDM4EALDH1A1MAPTPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336735-B | Urolithin compound, preparation method, pharmaceutical composition and application | 常州大学 | 2022-09-30 | — | — | CN | disclosed |