Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.85 |
| ▸ | PDE4A | P27815 | 5/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.44 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17559325 | 1.00 | PDE4B (0.85) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL20420874 | 1.00 | PDE4B (0.85) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL16046102 | 1.00 | PDE4B (0.85) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL19251711 | 0.95 | PDE4B (0.81) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL28422126 | 0.94 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL28422128 | 0.94 | PDE4B (0.76) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL28420638 | 0.93 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL28420639 | 0.93 | PDE4B (0.74) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL22129489 | 0.92 | PDE4B (0.85) | PDE4BPDE4APDE4CPDE4DPDE7A | |
| SCHEMBL22129492 | 0.92 | PDE4B (0.85) | PDE4BPDE4APDE4CPDE4DPDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001327-B | Crystal and pharmaceutical composition and application thereof | 伊莱利利公司 | 2022-09-02 | — | — | CN | claimed |
| CN-107001327-B | Crystal and pharmaceutical composition and application thereof | 伊莱利利公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-107001327-B | Crystal and pharmaceutical composition and application thereof | 伊莱利利公司 | 2022-09-02 | — | — | CN | disclosed |