Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285001 | 0.91 | ELANE (0.66) | ELANE | |
| SCHEMBL18619617 | 0.90 | PREP (0.53) | ELANEPREP | |
| SCHEMBL20484656 | 0.90 | PREP (0.53) | ELANEPREP | |
| SCHEMBL18620887 | 0.87 | PREP (0.50) | ELANEPREP | |
| SCHEMBL20485172 | 0.87 | PREP (0.50) | ELANEPREP | |
| SCHEMBL20484583 | 0.84 | POLB (0.54) | POLBSMN1; SMN2 | |
| SCHEMBL18620665 | 0.84 | POLB (0.54) | POLBSMN1; SMN2 | |
| SCHEMBL18620639 | 0.84 | CCR1 (0.53) | ELANEPREP | |
| SCHEMBL20484720 | 0.84 | CCR1 (0.53) | ELANEPREP | |
| SCHEMBL18619558 | 0.81 | ACE (0.62) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11458477-B2 | Evacuated blood collection tubes containing protease inhibitors for the assessment of contact system activation | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2022-10-04 | — | — | US | disclosed |