Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 19/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179014 | 1.00 | RET (0.39) | RETKDRRXFP1 | |
| SCHEMBL21179100 | 0.87 | RET (0.39) | RETKDRRXFP1 | |
| SCHEMBL29897206 | 0.87 | RET (0.39) | RETKDRRXFP1 | |
| SCHEMBL21178935 | 0.82 | RET (0.49) | RETKDR | |
| SCHEMBL21178936 | 0.82 | RET (0.49) | RETKDR | |
| SCHEMBL29897232 | 0.82 | RET (0.49) | RETKDR | |
| SCHEMBL24464378 | 0.78 | RET (0.41) | RETKDRRXFP1 | |
| SCHEMBL1483040 | 0.77 | RET (0.41) | RETKDRRXFP1 | |
| SCHEMBL24429585 | 0.77 | RET (0.43) | RETKDRRXFP1 | |
| SCHEMBL30071117 | 0.77 | RET (0.41) | RETKDRRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615514-B | Substituted pyrazolo [4,3-C ] pyridine compounds as RET kinase inhibitors | 奥瑞生物药品公司 | 2022-10-11 | — | — | CN | disclosed |