Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179039 | 1.00 | RET (1.00) | RET | |
| SCHEMBL29909576 | 0.90 | RET (1.00) | RET | |
| SCHEMBL21191361 | 0.90 | RET (1.00) | RET | |
| SCHEMBL21191364 | 0.88 | RET (1.00) | RET | |
| SCHEMBL29897219 | 0.88 | RET (1.00) | RET | |
| SCHEMBL21191371 | 0.87 | RET (1.00) | RET | |
| SCHEMBL21191357 | 0.86 | RET (0.75) | RET | |
| SCHEMBL21191359 | 0.83 | RET (1.00) | RET | |
| SCHEMBL21191346 | 0.83 | RET (0.80) | RET | |
| SCHEMBL21191306 | 0.83 | RET (1.00) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111615514-B | Substituted pyrazolo [4,3-C ] pyridine compounds as RET kinase inhibitors | 奥瑞生物药品公司 | 2022-10-11 | — | — | CN | disclosed |