SCHEMBL298980

SCHEMBL298980

Cc1nnc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31227322 0.79
SCHEMBL2210464 0.69 GAA (0.33)
SCHEMBL11148415 0.65
SCHEMBL5136319 0.65
SCHEMBL11201569 0.65
SCHEMBL7876460 0.65
SCHEMBL10961995 0.65
SCHEMBL282505 0.65
SCHEMBL349852 0.65
SCHEMBL5012245 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111995548-B Preparation method of cyano tertiary amine 河南省化工研究所有限责任公司 2022-09-02 CN claimed
CN-114805164-A Recycling method of 5-methyl-2-hydroxy-1, 3, 4-thiadiazole 法姆瑞斯医药科技(北京)有限公司 2022-07-29 CN claimed
CN-111995548-A Preparation method of cyano tertiary amine 河南省化工研究所有限责任公司 2020-11-27 CN claimed
US-12637451-B2 Amino quinazoline derivatives as P2X3 inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-26 US disclosed
US-20260137680-A1 NOVEL COMPOUNDS SITRYX THERAPEUTICS LTD (GB) 2026-05-21 US disclosed
EP-4716532-A2 BICYCLIC HETEROARYL COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-01 EP disclosed
US-12570655-B2 Cysteine covalent modifiers of AKT1 and uses thereof TERREMOTO BIOSCIENCES, INC. (US) 2026-03-10 US disclosed
WO-2025081045-A9 CYSTEINE COVALENT MODIFIERS OF AKT1 AND USES THEREOF TERREMOTO BIOSCIENCES, INC. (US) 2025-12-26 WO disclosed
US-20250388589-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO LTD (CN) 2025-12-25 US disclosed
EP-4651872-A1 COMPOUNDS, COMPOSITIONS AND METHODS OF USE TO TREAT HYPOPARATHYROIDISM AND OSTEOPOROSIS Septerna, Inc. (US) 2025-11-26 EP disclosed
US-20250346564-A1 INHIBITORS OF PARG ARASE THERAPEUTICS INC (US) 2025-11-13 US disclosed
EP-0398426-A1 Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
EP-0398425-A1 Antirhinoviral piperidinyl, pyrrolidinyl and piperazinyl alkylphenol ethers JANSSEN PHARMACEUTICA N.V. (BE) 1990-11-22 EP disclosed
US-4943580-A ANTIALLERGENS JANSSEN PHARMACEUTICA N.V. (BE) 1990-07-24 US disclosed
EP-0145037-B1 N-(BICYCLIC HETEROCYCLYL)-4-PIPERIDINAMINES JANSSEN PHARMACEUTICA N.V. (BE) 1989-01-18 EP disclosed
EP-0282133-A2 1-alkyl substituted benzimidazole derivatives JANSSEN PHARMACEUTICA N.V. (BE) 1988-09-14 EP disclosed
US-4634704-A HISTAMINE AND SEROTONINE ANTAGONISTS JANSSEN PHARMACEUTICA, N.V. (BE) 1987-01-06 US disclosed
EP-0145037-A2 N-(bicyclic heterocyclyl)-4-piperidinamines JANSSEN PHARMACEUTICA N.V. (BE) 1985-06-19 EP disclosed
US-4177272-A HYPOTENSIVE, VASODILATION, PARKINSON'S DISEASE SCIENCE UNION ET CIE (FR) 1979-12-04 US disclosed
US-3946000-A BACTERICIDES, POULTRY, ANIMALS BRISTOL-MYERS COMPANY (US) 1976-03-23 US disclosed