Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.56 |
| ▸ | KIT | P10721 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24197341 | 1.00 | BTK (0.56) | BTKKITFLT3EGFRLCK | |
| SCHEMBL28734217 | 0.92 | BTK (0.55) | BTKKITFLT3EGFRLCK | |
| SCHEMBL30415202 | 0.92 | BTK (0.58) | BTKKITFLT3EGFRLCK | |
| SCHEMBL24196657 | 0.92 | BTK (0.58) | BTKKITFLT3EGFRLCK | |
| SCHEMBL22720754 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK | |
| SCHEMBL22720892 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK | |
| SCHEMBL22720750 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK | |
| SCHEMBL24827868 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK | |
| SCHEMBL22720845 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK | |
| SCHEMBL22720728 | 0.91 | BTK (0.64) | BTKKITFLT3EGFRLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920746-A | BTK (BTK inhibitory or degrading agent) and application thereof in medicine | 四川海思科制药有限公司 | 2022-08-19 | — | — | CN | disclosed |