Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 20/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 19/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 12/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.42 |
| ▸ | CSNK2A3 | Q8NEV1 | 6/20 | 0.39 |
| ▸ | CLK2 | P49760 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25369875 | 1.00 | CSNK2A2 (0.44) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25369145 | 0.94 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL29900180 | 0.94 | CSNK2A2 (0.47) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL29900158 | 0.93 | CSNK2A2 (0.38) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25371849 | 0.93 | CSNK2A2 (0.39) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL29900346 | 0.93 | CSNK2A2 (0.39) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25372087 | 0.93 | CSNK2A2 (0.38) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25371668 | 0.91 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL29900184 | 0.91 | CSNK2A2 (0.46) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 | |
| SCHEMBL25370616 | 0.91 | CSNK2A2 (0.37) | CSNK2A2CSNK2BCSNK2A1PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | claimed |
| WO-2022185041-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2022-09-09 | — | — | WO | claimed |
| EP-4301752-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | Cambridge Enterprise Limited (GB) | 2024-01-10 | — | — | EP | disclosed |
| WO-2022185041-A1 | BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2022-09-09 | — | — | WO | disclosed |