Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10234057 | 0.90 | KCNJ1 (1.00) | KCNJ1KCNH2 | |
| Trifluoroacetic Acid SCHEMBL17360760 | 0.87 | KCNJ1 (0.80) | KCNJ1KCNH2 | |
| SCHEMBL2730746 | 0.85 | KCNH2 (0.71) | KCNJ1KCNH2 | |
| SCHEMBL16685019 | 0.84 | KCNJ1 (0.74) | KCNJ1KCNH2 | |
| SCHEMBL14782785 | 0.83 | KCNJ1 (0.85) | KCNJ1KCNH2 | |
| SCHEMBL2730748 | 0.82 | KCNJ1 (0.64) | KCNJ1KCNH2 | |
| SCHEMBL15210266 | 0.82 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| SCHEMBL15953883 | 0.82 | KCNJ1 (0.71) | KCNJ1KCNH2 | |
| SCHEMBL296919 | 0.82 | KCNJ1 (0.83) | KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL2731434 | 0.81 | KCNJ1 (0.81) | KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427444-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | Merck Sharp & Dohme Corp. (US) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010129379-A1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME CORP. (US) | 2010-11-11 | — | — | WO | disclosed |