SCHEMBL29900367

SCHEMBL29900367

CC(C)(C)OC(=O)NCCCCOCCOc1nc2cc(C(=O)O)ccc2c2cnccc12

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 18/20 0.49
CSNK2B P67870 18/20 0.49
CSNK2A1 P68400 13/20 0.49
PARP1 P09874 1/20 0.46
BRD4 O60885 1/20 0.46
HDAC1 Q13547 4/20 0.44
CSNK2A3 Q8NEV1 4/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25371343 1.00 CSNK2A2 (0.49) CSNK2A2CSNK2BCSNK2A1PARP1BRD4
SCHEMBL26049275 0.93 STING1 (0.48) CSNK2A2CSNK2BCSNK2A1PARP1BRD4
SCHEMBL30828723 0.88 CCNC (0.40) CSNK2A2CSNK2BCSNK2A1BRD4
SCHEMBL27374877 0.88 CCNC (0.40) CSNK2A2CSNK2BCSNK2A1BRD4
SCHEMBL30828704 0.87 CSNK2A2 (0.46) CSNK2A2CSNK2BCSNK2A1PARP1BRD4
SCHEMBL27375725 0.87 CSNK2A2 (0.46) CSNK2A2CSNK2BCSNK2A1PARP1BRD4
SCHEMBL25369436 0.87 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1BRD4HDAC1
SCHEMBL31092869 0.87 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1BRD4HDAC1
SCHEMBL25369998 0.87 CSNK2A2 (0.50) CSNK2A2CSNK2BCSNK2A1BRD4HDAC1
SCHEMBL30803388 0.87 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584268-A1 PRODRUGS Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
EP-4584265-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
WO-2024052693-A1 PRODRUGS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
WO-2024052690-A1 NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
EP-4301752-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF Cambridge Enterprise Limited (GB) 2024-01-10 EP disclosed
WO-2022185041-A1 BENZO[C][2,6]NAPHTHYRIDINE DERIVATIVES, COMPOSITIONS AND THERAPEUTIC USES THEREOF CAMBRIDGE ENTERPRISE LIMITED (GB) 2022-09-09 WO disclosed