Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.39 |
| ▸ | MC1R | Q01726 | 5/20 | 0.39 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23924180 | 0.88 | TACR1 (0.40) | TRPV1KCNH2 | |
| SCHEMBL29900664 | 0.87 | KDM4E (0.45) | TRPV1MC4RMC5RMC3RSMN1; SMN2 | |
| SCHEMBL29900750 | 0.87 | KDM4E (0.45) | TRPV1MC4RMC5RMC3RSMN1; SMN2 | |
| SCHEMBL23951633 | 0.86 | TACR1 (0.52) | TRPV1MC4R | |
| SCHEMBL23951339 | 0.83 | KCNH2 (0.54) | TRPV1KCNH2 | |
| Hydrochloric Acid SCHEMBL23924251 | 0.83 | KCNH2 (0.53) | TRPV1KCNH2 | |
| Hydrochloric Acid SCHEMBL30098491 | 0.83 | KCNH2 (0.53) | TRPV1KCNH2 | |
| SCHEMBL29900751 | 0.80 | MC1R (0.44) | MC1RSMN1; SMN2 | |
| SCHEMBL23924412 | 0.77 | KDM4E (0.38) | TRPV1SMN1; SMN2 | |
| SCHEMBL23924411 | 0.77 | KDM4E (0.38) | TRPV1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | TES PHARMA S.R.L. (IT) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220213061-A9 | HETEROCYCLIC COMPOUNDS FOR MODULATING NR2F6 | NR2E3, NR2F2, NR2C2 | TRPV1 4072/4885MC1R 720/4885MC4R 1690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.