Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 7/20 | 0.51 |
| ▸ | SLC9A1 | P19634 | 6/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29901094 | 0.85 | GRM2 (0.55) | GRM2SLC9A1TLR8NPC1 | |
| SCHEMBL19911456 | 0.84 | GRM2 (0.70) | GRM2SLC9A1TLR8NPC1 | |
| SCHEMBL4233106 | 0.84 | GRM2 (0.49) | GRM2SLC9A1NPC1 | |
| SCHEMBL17291776 | 0.81 | GRM2 (0.43) | GRM2SLC9A1NPC1 | |
| SCHEMBL19911457 | 0.81 | GRM2 (0.69) | GRM2SLC9A1TLR8NPC1 | |
| SCHEMBL30643299 | 0.78 | GRM2 (0.48) | GRM2SLC9A1TLR8NPC1 | |
| SCHEMBL17828279 | 0.77 | GRM2 (0.67) | GRM2SLC9A1TLR8NPC1 | |
| SCHEMBL30620226 | 0.77 | GRM2 (0.48) | GRM2SLC9A1NPC1 | |
| SCHEMBL24296919 | 0.77 | GRM2 (0.49) | GRM2SLC9A1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL974069 | 0.77 | GRM2 (0.40) | GRM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151538-A | Macrocyclic compounds, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-10-04 | — | — | CN | disclosed |