Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 5/20 | 0.57 |
| ▸ | JAK3 | P52333 | 5/20 | 0.57 |
| ▸ | TYK2 | P29597 | 2/20 | 0.57 |
| ▸ | JAK2 | O60674 | 4/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 14/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
| ▸ | CD69 | Q07108 | 1/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.48 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.48 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275614 | 1.00 | JAK1 (0.57) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23275683 | 0.90 | JAK1 (0.57) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23275660 | 0.87 | JAK1 (0.63) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23275745 | 0.86 | BTK (0.53) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL29901154 | 0.85 | JAK1 (0.63) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23281855 | 0.85 | JAK1 (0.63) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL27228445 | 0.85 | JAK3 (0.76) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL29901144 | 0.85 | JAK1 (0.60) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23281905 | 0.85 | JAK1 (0.60) | JAK1JAK3TYK2JAK2STAT3 | |
| SCHEMBL23275647 | 0.83 | JAK1 (0.58) | JAK1JAK3TYK2JAK2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4050009-A1 | SMALL MOLECULE COMPOUND | Technoderma Medicines Pte Ltd (CN) | 2022-08-31 | — | — | EP | disclosed |