Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 1/20 | 0.68 |
| ▸ | YAP1 | P46937 | 1/20 | 0.68 |
| ▸ | TNNI3K | Q59H18 | 10/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 5/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20766283 | 1.00 | TEAD1 (0.68) | TEAD1YAP1TNNI3KEPAS1KAT5 | |
| SCHEMBL20766326 | 0.90 | TEAD1 (0.70) | TEAD1YAP1TNNI3KKAT5BRAF | |
| SCHEMBL25790393 | 0.90 | TEAD1 (0.67) | TEAD1YAP1TNNI3KEPAS1KAT5 | |
| SCHEMBL20766333 | 0.90 | TEAD1 (0.69) | TEAD1YAP1TNNI3KEPAS1KAT5 | |
| SCHEMBL20766622 | 0.88 | TEAD1 (0.76) | TEAD1YAP1TNNI3K | |
| SCHEMBL20766405 | 0.85 | TEAD1 (0.66) | TEAD1YAP1TNNI3KEPAS1BRAF | |
| SCHEMBL20766836 | 0.85 | TEAD1 (0.74) | TEAD1YAP1TNNI3KKAT5BRAF | |
| SCHEMBL25790336 | 0.84 | TEAD1 (0.77) | TEAD1YAP1TNNI3KBRAF | |
| SCHEMBL25790356 | 0.84 | TEAD1 (0.61) | TEAD1YAP1TNNI3KEPAS1BRAF | |
| SCHEMBL20766267 | 0.83 | TEAD1 (0.74) | TEAD1YAP1TNNI3KEPAS1KAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542315-B | Benzosulfonyl compounds | 维瓦斯治疗公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-3691623-B1 | BENZOSULFONYL COMPOUNDS | VIVACE THERAPEUTICS INC (US) | 2022-10-05 | — | — | EP | disclosed |