Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 17/20 | 0.69 |
| ▸ | CHUK | O15111 | 17/20 | 0.69 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986595 | 0.95 | IKBKB (0.75) | IKBKBCHUKCSNK1DMAPK14CYP2C9 | |
| SCHEMBL2993450 | 0.90 | IKBKB (0.68) | IKBKBCHUKCSNK1DMAPK14 | |
| SCHEMBL2986596 | 0.89 | IKBKB (0.64) | IKBKBCHUKCSNK1DMAPK14BRAF | |
| SCHEMBL2982305 | 0.86 | IKBKB (0.81) | IKBKBCHUK | |
| SCHEMBL2993449 | 0.86 | IKBKB (0.59) | IKBKBCHUKCSNK1DMAPK14CYP2C9 | |
| SCHEMBL2990350 | 0.84 | IKBKB (0.59) | IKBKBCHUKCSNK1DMAPK14 | |
| SCHEMBL2994240 | 0.84 | IKBKB (0.58) | IKBKBCHUKCSNK1DMAPK14CYP2C9 | |
| SCHEMBL3413884 | 0.83 | IKBKB (0.82) | IKBKBCHUKCYP2C9 | |
| Trifluoroacetic Acid SCHEMBL3413869 | 0.83 | IKBKB (0.87) | IKBKBCHUKSLC22A12 | |
| Formic Acid SCHEMBL2981787 | 0.82 | IKBKB (0.54) | IKBKBCHUKCSNK1DMAPK14BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100179139-A1 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | BAMBOROUGH PAUL | 2010-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179139-A1 | PYRROLOPYRIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | NFKBIA, PACSIN2, MAP3K2 | IKBKB 11/4885CHUK 22/4885CSNK1D 124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.