Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29903128 | 1.00 | IDO1 (0.43) | IDO1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL23409308 | 1.00 | IDO1 (0.43) | IDO1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7019157 | 0.84 | HSD17B10 (0.53) | IDO1MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL30118104 | 0.81 | CDC25B (0.47) | IDO1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL23409342 | 0.81 | CDC25B (0.47) | IDO1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1619337 | 0.78 | HSD17B10 (0.64) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL29937467 | 0.78 | HSD17B10 (0.64) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6914207 | 0.77 | HSD17B10 (0.62) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6913636 | 0.77 | HSD17B10 (0.62) | MEN1KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL6914711 | 0.77 | HSD17B10 (0.62) | MEN1KMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065583-A1 | A COMPOUND HAVING INHIBITORY ACTIVITY AGAINST KRAS G12D MUTATION | Taiho Pharmaceutical Co., Ltd. (JP) | 2022-10-05 | — | — | EP | disclosed |