Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 4/20 | 0.38 |
| ▸ | CCR4 | P51679 | 7/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26980783 | 1.00 | SGK1 (0.38) | SGK1CCR4NR4A2NR3C1MEN1 | |
| SCHEMBL26980306 | 0.92 | SGK1 (0.38) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL29903772 | 0.92 | SGK1 (0.38) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL20339157 | 0.87 | SGK1 (0.42) | SGK1CCR4NR4A2SLC40A1KAT6A | |
| SCHEMBL20355155 | 0.87 | SGK1 (0.38) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL29903736 | 0.86 | CCR4 (0.38) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL26980252 | 0.86 | CCR4 (0.38) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL20344324 | 0.86 | CCR4 (0.44) | SGK1CCR4NR4A2MEN1KMT2A | |
| SCHEMBL29903540 | 0.85 | CCR4 (0.38) | SGK1CCR4NR4A2NR3C1MEN1 | |
| SCHEMBL26980207 | 0.85 | CCR4 (0.38) | SGK1CCR4NR4A2NR3C1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558496-A1 | NOVEL PYRIMIDINYL AND TRIAZINYL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024017863-A1 | NOVEL PYRIMIDINYL AND TRIAZINYL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-01-25 | — | — | WO | disclosed |
| EP-4298092-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2024-01-03 | — | — | EP | disclosed |
| CN-116829550-A | Pyrimidine-2-ylsulfonamide derivatives | 豪夫迈·罗氏有限公司 | 2023-09-29 | — | — | CN | disclosed |
| WO-2022180136-A1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2022-09-01 | — | — | WO | disclosed |