Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23461169 | 1.00 | APP (0.47) | APPMAPK1HTTEGFRLMNA | |
| SCHEMBL557825 | 0.86 | APP (0.51) | APPMAPK1HTTEGFRLMNA | |
| SCHEMBL557824 | 0.83 | APP (0.51) | APPMAPK1HTTEGFRLMNA | |
| SCHEMBL3952920 | 0.78 | HPGD (0.49) | APPLMNATMIGD3ADORA2AADORA2B | |
| SCHEMBL2323296 | 0.75 | KDM4E (0.43) | MAPK1HTTEGFRLMNASLC29A1 | |
| SCHEMBL3956502 | 0.75 | HPGD (0.49) | APPLMNATMIGD3ADORA2AADORA2B | |
| SCHEMBL6209927 | 0.73 | APP (0.57) | APPMAPK1HTTEGFRLMNA | |
| SCHEMBL23852988 | 0.72 | CCNE1 (0.38) | HDAC3HDAC1HDAC6KMT2A | |
| SCHEMBL23461156 | 0.72 | TAAR1 (0.49) | APPMAPK1HTTEGFRLMNA | |
| SCHEMBL3953432 | 0.72 | NPC1 (0.50) | APPBCHEACHETMIGD3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115052604-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2022-09-13 | — | — | CN | disclosed |