SCHEMBL29904550

SCHEMBL29904550

CC(C)(C)N1CC(C(=O)O)C(c2ccc(F)cc2F)C1

nearest known ligand 0.64

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MC4R P32245 17/20 0.64
MC3R P41968 7/20 0.62
MC5R P33032 7/20 0.62
MC1R Q01726 7/20 0.62
KCNH2 Q12809 4/20 0.62
PRCP P42785 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3170759 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL71984 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL71981 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL15252713 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL91103 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL70497 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL30593923 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
SCHEMBL1920391 1.00 MC4R (0.64) MC4RMC3RMC5RMC1RKCNH2
Hydrochloric Acid SCHEMBL4939210 0.99 MC4R (0.63) MC4RMC3RMC5RMC1RKCNH2
Hydrochloric Acid SCHEMBL4939214 0.99 MC4R (0.63) MC4RMC3RMC5RMC1RKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022182194-A1 MELANOCORTIN-4 RECEPTOR AGONIST 주식회사 엘지화학 2022-09-01 WO disclosed