Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.47 |
| ▸ | INSR | P06213 | 4/20 | 0.47 |
| ▸ | IGF1R | P08069 | 4/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906574 | 1.00 | EGFR (0.53) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906499 | 0.92 | EGFR (0.45) | EGFRALKINSRIGF1R | |
| SCHEMBL26906828 | 0.88 | EGFR (0.54) | EGFRALKINSRIGF1RMET | |
| SCHEMBL29904646 | 0.87 | EGFR (0.62) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906906 | 0.87 | EGFR (0.62) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906728 | 0.85 | ALK (0.63) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906761 | 0.85 | EGFR (0.66) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906904 | 0.85 | EGFR (0.60) | EGFRALKINSRIGF1RMET | |
| SCHEMBL30860293 | 0.85 | EGFR (0.60) | EGFRALKINSRIGF1RMET | |
| SCHEMBL26906939 | 0.84 | EGFR (0.55) | EGFRALKINSRIGF1RMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | claimed |
| WO-2022211573-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2022-10-06 | — | — | WO | disclosed |