Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.86 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.57 |
| ▸ | F11 | P03951 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.49 |
| ▸ | CTRL | P40313 | 1/20 | 0.49 |
| ▸ | CTRB2 | Q6GPI1 | 1/20 | 0.49 |
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29905691 | 0.92 | F2 (1.00) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL29905358 | 0.91 | F2 (0.82) | F2KLKB1 | |
| SCHEMBL18039854 | 0.90 | F2 (1.00) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL18039776 | 0.87 | F2 (0.90) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL20473859 | 0.86 | F2 (0.85) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL18039911 | 0.85 | F2 (0.93) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL20473866 | 0.83 | F2 (0.83) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL29905340 | 0.82 | F2 (0.72) | F2KLKB1 | |
| SCHEMBL18039822 | 0.82 | F2 (0.77) | F2KLKB1F11CTRB1CTRL | |
| SCHEMBL29905258 | 0.82 | F2 (0.77) | F2KLKB1F11CTRB1CTRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | claimed |
| EP-3261639-B1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INT CORPORATION (US) | 2022-08-24 | — | — | EP | disclosed |